ea0040p5 | (1) | ESEBEC2016
Rusinek Dagmara
, Swierniak Michal
, Chmielik Ewa
, Kowal Monika
, Kowalska Malgorzata
, Cyplinska Renata
, Czarniecka Agnieszka
, Piglowski Wojciech
, Korfanty Joanna
, Chekan Mykola
, Jarzab Michal
, Krajewska Jolanta
, Szpak-Ulczok Sylwia
, Widłak Wieslawa
, Jarzab Barbara
Introduction: BRAFV600E mutation is the most frequent alteration in papillary thyroid carcinoma (PTC). Although its relation to factors of poor prognosis was demonstrated in many studies the use of BRAF as a predictive marker in clinical treatment of PTC patients is controversial. The aim of our study was to analyze molecular consequences of BRAFV600E mutation in a transgenic mouse model performed for this purpose and to refer the obtained results to...